white rabbit
Cruelty Free Cleaning bill introduced in New York 

Cruelty Free Cleaning bill introduced in New York 

September 3, 2026
Upper Tribunal says secrecy around UK animal experiments is unlawful

Upper Tribunal says secrecy around UK animal experiments is unlawful

September 1, 2026
Merton College
Creating change for animals at the Oxford Centre for Animal Ethics Summer School

Creating change for animals at the Oxford Centre for Animal Ethics Summer School

August 27, 2026
Europe takes action to phase out animal testing of Botox products
Europe takes action to phase out animal testing of Botox products

Europe takes action to phase out animal testing of Botox products

August 19, 2026
Guinea Pig
Building on FDA Modernization to Replace Animal Tests

Building on FDA Modernization to Replace Animal Tests

August 14, 2026
Whit Rabbit
We take our fight for freedom of information to the Royal Courts of Justice

We take our fight for freedom of information to the Royal Courts of Justice

July 29, 2026
Andy Burnham
Government must speed-up implementation of animal testing strategy

Government must speed-up implementation of animal testing strategy

July 23, 2026
2.54 million animal tests in Great Britain in 2025 
2.54 million animal tests in Great Britain in 2025

2.54 million animal tests in Great Britain in 2025

July 9, 2026
New dashboard will reduce global animal testing
New dashboard will reduce global animal testing

New dashboard will reduce global animal testing

July 3, 2026
Beagle
U.S. Appropriations Bill encourages NIH to promote non-animal research

U.S. Appropriations Bill encourages NIH to promote non-animal research

June 26, 2026
Vivotecnia investigation
We are appealing against acquittal in Vivotecnia trial

We are appealing against acquittal in Vivotecnia trial

June 24, 2026
Primate.
U.S. agencies make progress in replacing animal testing

U.S. agencies make progress in replacing animal testing

June 18, 2026
Second Species Workshop
Is the tide turning on second species testing?

Is the tide turning on second species testing?

June 15, 2026
Kiera Walsh
Lionesses legend Keira Walsh MBE supports Move for the Millions

Lionesses legend Keira Walsh MBE supports Move for the Millions

May 22, 2026
Vivotecnia
Criminal trial of two Vivotecnia workers begins today

Criminal trial of two Vivotecnia workers begins today

May 7, 2026
Our Deputy Director of Science and Regulatory Affairs, Dr Laura Alvarez.
The RAT List makes its debut at the 2026 Society of Toxicology meeting

The RAT List makes its debut at the 2026 Society of Toxicology meeting

April 8, 2026
Guinea Pig
Latest figures show need for ambition in EU phase-out plans

Latest figures show need for ambition in EU phase-out plans

April 1, 2026
The Cruelty Free International Approval Programme – A New Chapter Begins
The Cruelty Free International Approval Programme – A New Chapter Begins

The Cruelty Free International Approval Programme – A New Chapter Begins

March 16, 2026
Animals still die in the name of beauty
Animals still die in the name of beauty – 13 years after EU cosmetics testing bans

Animals still die in the name of beauty – 13 years after EU cosmetics testing bans

March 11, 2026
Peaceful protest against animal testing facilities has been restricted 
Peaceful protest against animal testing facilities has been severely restricted 

Peaceful protest against animal testing facilities has been severely restricted 

February 5, 2026
U.S. Environmental Protection Agency renews deadline to end animal testing 
U.S. Environmental Protection Agency renews deadline to end animal testing 

U.S. Environmental Protection Agency renews deadline to end animal testing 

January 27, 2026
Dog Sitting
We urge House of Lords to reject Public Order Act amendments 

We urge House of Lords to reject Public Order Act amendments 

January 15, 2026
Cat looking outside
EU Commission launches improved database for non-technical summaries of animal experiments

EU Commission launches improved database for non-technical summaries of animal experiments

January 13, 2026
Rabbit in grass
Rabbit pyrogen test has been deleted from EU medicines rulebook

Rabbit pyrogen test has been deleted from EU medicines rulebook

January 8, 2026
MP of the Year Alex Mayer
Alex Mayer named our ‘MP of the Year’

Alex Mayer named our ‘MP of the Year’

January 5, 2026
Mouse
We applaud introduction of the Replace Act

We applaud introduction of the Replace Act

December 18, 2025
Animals in Science Regulation Unit (ASRU)
Animals in Science Regulation Unit Report

Animals in Science Regulation Unit Report

December 16, 2025
Brown Dog Statue
40th anniversary of Brown Dog statue

40th anniversary of Brown Dog statue

December 12, 2025
We welcome FDA moves to cut primate testing as roadmap begins to take shape
We welcome FDA moves to cut primate testing as roadmap begins to take shape

We welcome FDA moves to cut primate testing as roadmap begins to take shape

December 5, 2025
CDC’s end of primate experiments must include rehoming plan
CDC’s end of primate experiments must include rehoming plan

CDC’s end of primate experiments must include rehoming plan

December 3, 2025
Detail on promised funding for animal testing strategy still needed
Detail on promised funding for animal testing strategy still needed

Detail on promised funding for animal testing strategy still needed

November 25, 2025
Beagle
Government launches bold new plan to replace animal testing

Government launches bold new plan to replace animal testing

November 11, 2025
Grey Rat
2.64 million animal tests in Great Britain in 2024 

2.64 million animal tests in Great Britain in 2024 

October 23, 2025
UK Animals in Science Committee recommends greater transparency in animal testing
UK Animals in Science Committee recommends greater transparency in animal testing

UK Animals in Science Committee recommends greater transparency in animal testing

October 10, 2025
Dame Jane Goodall
The world loses a unique and powerful voice. Dame Jane Goodall 1934-2025

The world loses a unique and powerful voice. Dame Jane Goodall 1934-2025

October 3, 2025
Forever home funding now covered by NIH grants
Forever home funding now covered by NIH grants

Forever home funding now covered by NIH grants

October 3, 2025
Scientists
We welcome latest NIH move to accelerate the use of non-animal methods

We welcome latest NIH move to accelerate the use of non-animal methods

September 26, 2025
Cruelty Free International at WC13: Highlights from Rio
Cruelty Free International at WC13: Highlights from Rio

Cruelty Free International at WC13: Highlights from Rio

September 18, 2025
Sharing our expertise at World Congress
Sharing our expertise at World Congress

Sharing our expertise at World Congress

August 14, 2025
Guinea Pig
Canada Publishes Final Strategy on Animal Testing – But Gaps Remain

Canada Publishes Final Strategy on Animal Testing – But Gaps Remain

July 25, 2025
NIH stops funding new projects which focus only on animal testing
NIH stops funding new projects which focus only on animal testing

NIH stops funding new projects which focus only on animal testing

July 10, 2025
Bloomberg’s ‘Monkey Laundering' report wins Outstanding Short Documentary
Our macaque trade investigative work features in Emmy award-winning documentary

Our macaque trade investigative work features in Emmy award-winning documentary

July 7, 2025
Webinar shows potential for homing animals after use in laboratories
Webinar shows potential for homing animals after use in laboratories

Webinar shows potential for homing animals after use in laboratories

July 3, 2025
Prime Video España release d documentary on animal abuse at Vivotecnia
Prime Video España release d documentary on animal abuse at Vivotecnia

Prime Video España release d documentary on animal abuse at Vivotecnia

June 27, 2025
We are a sponsor of 13th World Congress on Alternatives and Animal Use in the Life Sciences 
We are a sponsor of 13th World Congress on Alternatives and Animal Use in the Life Sciences 

We are a sponsor of 13th World Congress on Alternatives and Animal Use in the Life Sciences 

June 10, 2025
Governor rejects Nevada cruelty-free cleaning bill
Governor rejects Nevada cruelty-free cleaning bill

Governor rejects Nevada cruelty-free cleaning bill

June 6, 2025
Nevada one step from cleaning-up cruelty
Nevada one step from cleaning-up cruelty

Nevada one step from cleaning-up cruelty

May 23, 2025
Our science team give presentations at key European forums to advance animal-free science
Our science team give presentations at key European forums to advance animal-free science

Our science team give presentations at key European forums to advance animal-free science

May 22, 2025
We meet with UK Science Minister Lord Vallance on phase-out of animal testing
We meet with UK Science Minister Lord Vallance on phase-out of animal testing

We meet with UK Science Minister Lord Vallance on phase-out of animal testing

May 15, 2025
We took our updated Replace Animal Tests (RAT) List to Parliament
We took our updated Replace Animal Tests (RAT) List to Parliament

We took our updated Replace Animal Tests (RAT) List to Parliament

May 8, 2025
Several of Parliament’s most active and committed supporters of animal welfare, from across the political spectrum, joined us in the House of Commons to learn how a number of outdated and unnecessary animal tests could be ended immediately, through our RAT (Replace Animal Tests) List. In a productive roundtable discussion, the MPs were shown how six animal tests – which use approximately 80,000 animals every year – are still conducted in the UK despite the availability of appropriate non-animal replacements. The detailed and well-informed session covered what the six tests on animals involve, the barriers to progress, and practical steps for securing an end to the unacceptable practise of testing on animals where replacements are available. Those present included Steve Race, a member of the Science, Innovation and Technology Committee; Alex Mayer, who played a leading role in our petition to the United Nations for a global ban on animal testing for cosmetics, in partnership with The Body Shop, which received eight million signatures to become the largest animal-related petition in history; and Irene Campbell, who Chairs the All Party Parliamentary Group on Phasing Out Animal Experiments in Medical Research, and led the recent debate on banning testing on dogs. In recent years, the development of non-animal methods has increased significantly, and they can now replace, wholly or in part, a number of tests on animals across several product sectors. However, our experience has been that actually replacing tests on animals takes much longer than it should. We have seen how non-animal methods available for assessing skin irritation, skin sensitisation and batch safety have taken years to be adopted and we know that tests on animals are still being conducted to provide this information. This is unacceptable. In many cases, the problem lies with a lack of clarity from, and enforcement by, regulatory authorities, as well as the absence of a joined-up approach for acceptance of non-animal methods around the world. Since non-animal tests can be cheaper, faster and more accurate than the tests on animals they replace, it is in the interests of animal welfare and good science to speed up their acceptance and to expand their use. Overcoming these remaining hurdles, so that these tests on animals can finally be fully replaced, is a matter of urgency. The six tests we discussed were for the assessment of skin irritation, skin sensitisation and eye irritation; routine batch testing of veterinary vaccines; potency testing of Botox samples; and the production of antibodies. Botox batch testing involves injecting Botulinum toxin into the abdomens of mice. Over three days they become increasingly paralysed, and if left the mice given the higher-level dose will slowly suffocate to death. Approximately half of the mice die during the test and all survivors are killed at the end of the test. Nearly 50,000 of these tests were carried out in the UK in 2023, despite the world’s major Botox manufacturers developing an alternative cell-based test. For antibody production, animals – including mice, rabbits, sheep, and goats – are used as ‘factories’ to generate large numbers of antibodies. An injection stimulates the animal’s immune system to produce specific types of antibodies – but this often causes harmful side effects before their blood is taken to harvest the antibodies. Animals are killed when they are no longer useful. Phage display technology – awarded the 2018 Nobel Prize in Chemistry and endorsed in 2020 by the EU Reference Laboratory for alternatives to animal testing – can be used to produce a wide range of antibodies that are of higher quality, more stable, more relevant and more reproducible than the antibodies produced in animals. They are also much faster and cheaper to produce. See the full RAT (Replace Animal Tests) List on our website. Our Head of Public Affairs, Dylan Underhill, said: “People may assume that tests on animals which have non-animal replacements available are no longer conducted, or at least rarely – but the reality is that such tests can continue, and even increase long after the adoption of suitable alternative methods. It was great to see MPs engaging with the issues and statistics behind our RAT List – politicians can play a vital role in overcoming the problems which prevent the adoption of new non-animal tests. This isn’t just about science, it’s about political will too. With the government working on its manifesto commitment to phase-out animal testing, ending these six tests represents a significant but easily-achieved first step towards that aim.”
New study reveals scale and severity of ‘force-feeding’ chemicals to animals during tests

New study reveals scale and severity of ‘force-feeding’ chemicals to animals during tests

May 7, 2025
e applaud new National Institutes of Health initiatives to prioritize human-based research
We applaud new National Institutes of Health initiatives to prioritize human-based research

We applaud new National Institutes of Health initiatives to prioritize human-based research

May 2, 2025
Government insists that animal testing remains necessary – for now
Government insists that animal testing remains necessary – for now

Government insists that animal testing remains necessary – for now

April 30, 2025
Nevada bill to restrict animal testing for household cleaning products passes Senate 
Nevada bill to restrict animal testing for household cleaning products passes Senate 

Nevada bill to restrict animal testing for household cleaning products passes Senate 

April 25, 2025
U.S. FDA unveils new roadmap to replace animal testing 
U.S. FDA unveils new roadmap to replace animal testing

U.S. FDA unveils new roadmap to replace animal testing

April 15, 2025
You are here: We ask the European Commission to strengthen the EU ban on animal testing for cosmetics
We ask the European Commission to strengthen the EU ban on animal testing for cosmetics

We ask the European Commission to strengthen the EU ban on animal testing for cosmetics

March 31, 2025
Society of Toxicology annual meeting
Advancements in non-animal testing highlighted at Society of Toxicology annual meeting

Advancements in non-animal testing highlighted at Society of Toxicology annual meeting

March 25, 2025
Animals still die in the name of beauty – 12 years after EU cosmetics testing bans
Animals still die in the name of beauty – 12 years after EU cosmetics testing bans

Animals still die in the name of beauty – 12 years after EU cosmetics testing bans

March 11, 2025
UK Home Office seeks advice to improve transparency in animal testing
UK Home Office seeks advice to improve transparency in animal testing

UK Home Office seeks advice to improve transparency in animal testing

March 7, 2025
We applaud the re-introduction of the U.S. Humane Cosmetics Act
We applaud the re-introduction of the U.S. Humane Cosmetics Act

We applaud the re-introduction of the U.S. Humane Cosmetics Act

March 6, 2025
Bill introduced in Nevada to Clean Up Cruelty
Bill introduced in Nevada to Clean Up Cruelty

Bill introduced in Nevada to Clean Up Cruelty

March 6, 2025
Give your HEARTS to animals this Valentine’s Day
Give your HEARTS to animals this Valentine’s Day

Give your HEARTS to animals this Valentine’s Day

February 14, 2025
USDA report reveals alarming rise in painful animal experiment
USDA report reveals alarming rise in painful animal experiments

USDA report reveals alarming rise in painful animal experiments

January 27, 2025
2024 round-up: our influence continues throughout the year of the election
2024 round-up: our influence continues throughout the year of the election

2024 round-up: our influence continues throughout the year of the election

January 10, 2025
About Animal Testing
Huge increase in reported number of animals harmed in breaches of UK animal protection law

Huge increase in reported number of animals harmed in breaches of UK animal protection law

December 20, 2024
Labour MP urges government action at our House of Commons reception
Labour MP urges government action at our House of Commons reception

Labour MP urges government action at our House of Commons reception

December 20, 2024
Government wishes everyone a cruelty-free Christmas! 
Government wishes everyone a cruelty-free Christmas! 

Government wishes everyone a cruelty-free Christmas! 

December 13, 2024
We sign open letter urging progress in government phase-out commitment 
We sign open letter urging progress in government phase-out commitment 

We sign open letter urging progress in government phase-out commitment 

December 4, 2024
We contribute to plans to reshape animal testing in Canada
We contribute to plans to reshape animal testing in Canada

We contribute to plans to reshape animal testing in Canada

December 2, 2024
Primate.
Report shows inadequate justification for primate tests

Report shows inadequate justification for primate tests

November 6, 2024
We welcome government focus on Life Sciences
We welcome government focus on Life Sciences

We welcome government focus on Life Sciences

October 31, 2024
Taking our cause to the Capitol
Taking our cause to the Capitol

Taking our cause to the Capitol

October 11, 2024
Sharing our vision of a cruelty-free future in Liverpool
Sharing our vision of a cruelty-free future in Liverpool

Sharing our vision of a cruelty-free future in Liverpool

September 25, 2024
Patrick Vallance to lead government creation of Roadmap towards animal testing phase-out
Patrick Vallance to lead government creation of Roadmap towards animal testing phase-out

Patrick Vallance to lead government creation of Roadmap towards animal testing phase-out

September 24, 2024
Home Office testing stats continue to show slow fall
Home Office testing stats continue to show slow fall

Home Office testing stats continue to show slow fall

September 12, 2024
We publish ‘First Steps’ report on the phase-out of animal testing in the UK
We publish ‘First Steps’ report on the phase-out of animal testing in the UK

We publish ‘First Steps’ report on the phase-out of animal testing in the UK

July 30, 2024
We are primed to support the animal testing phase out despite Kings Speech omission
We are primed to support the animal testing phase out despite Kings Speech omission

We are primed to support the animal testing phase out despite Kings Speech omission

July 17, 2024
We welcome  Labour Party’s pledge to phase out animal testing 
We welcome  Labour Party’s pledge to phase out animal testing 

We welcome  Labour Party’s pledge to phase out animal testing 

July 14, 2024
We look forward to the new Labour government’s plans to phase out animal testing
We look forward to the new Labour government’s plans to phase out animal testing

We look forward to the new Labour government’s plans to phase out animal testing

July 5, 2024
One week to go: what have the election manifestos said about animal testing?
One week to go: what have the election manifestos said about animal testing?

One week to go: what have the election manifestos said about animal testing?

June 27, 2024
We engage in key meetings working to end animal testing in Europe and beyond
We engage in key meetings working to end animal testing in Europe and beyond

We engage in key meetings working to end animal testing in Europe and beyond

June 24, 2024
Take action for animals with our General Election Supporters Pack
Take action for animals with our General Election Supporters Pack

Take action for animals with our General Election Supporters Pack

June 18, 2024
‘Forever Against Animal Testing’ wins campaign award
‘Forever Against Animal Testing’ wins campaign award

‘Forever Against Animal Testing’ wins campaign award

June 17, 2024
Ask your Parliamentary Candidates to support the end of animal testing
Ask your Parliamentary Candidates to support the end of animal testing

Ask your Parliamentary Candidates to support the end of animal testing

June 10, 2024
Tell your MP how important it is to end animal testing in the UK
Another sharp rise in reports of non-compliance with laws protecting animals in UK laboratories

Another sharp rise in reports of non-compliance with laws protecting animals in UK laboratories

May 9, 2024
Levels of animal suffering continue to be poorly reported
Levels of animal suffering continue to be poorly reported

Levels of animal suffering continue to be poorly reported

May 7, 2024
Webinar examines the release of animals from laboratories for adoption
Webinar examines the release of animals from laboratories for adoption

Webinar examines the release of animals from laboratories for adoption

May 2, 2024
We engage with the European Medicines Agency on their workplan goals
We engage with the European Medicines Agency on their workplan goals

We engage with the European Medicines Agency on their workplan goals

April 9, 2024
We showcase innovative science at US Capitol to support legislation to replace the use of animals
We showcase innovative science at US Capitol to support legislation to replace the use of animals

We showcase innovative science at US Capitol to support legislation to replace the use of animals

March 15, 2024
Budget a missed opportunity for UK life sciences
Budget a missed opportunity for UK life sciences

Budget a missed opportunity for UK life sciences

March 7, 2024
r Association calls for the Advancement of Non-Animal Research and Testing Methods You are here: American Bar Association calls for the Advancement of Non-Animal Research and Testing Methods
American Bar Association calls for the Advancement of Non-Animal Research and Testing Methods

American Bar Association calls for the Advancement of Non-Animal Research and Testing Methods

March 1, 2024
Cruelty Free Europe ask MEPs to Pledge Cruelty-Free
Cruelty Free Europe ask MEPs to Pledge Cruelty-Free

Cruelty Free Europe ask MEPs to Pledge Cruelty-Free

February 28, 2024
HEARTS Act inspires NIH investment in non-animal research methods
HEARTS Act inspires NIH investment in non-animal research methods

HEARTS Act inspires NIH investment in non-animal research methods

February 26, 2024
UK Government to increase funding for 3Rs and publish plans to reduce use of animals in science
UK Government to increase funding for 3Rs and publish plans to reduce use of animals in science

UK Government to increase funding for 3Rs and publish plans to reduce use of animals in science

February 21, 2024
We urge the Prime Minister and 7 political parties to make election commitments on animal testing
We urge the Prime Minister and 7 political parties to make election commitments on animal testing

We urge the Prime Minister and 7 political parties to make election commitments on animal testing

February 19, 2024
MPs commit to our #PledgeCrueltyFree campaign
MPs commit to our #PledgeCrueltyFree campaign

MPs commit to our #PledgeCrueltyFree campaign

February 1, 2024