About the campaign: setting the scene

Chemicals are all around us, present in materials such as plastic and in everyday items from household cleaners and DIY products to furniture. Hundreds of thousands of animals worldwide are used every year to test the safety of chemicals, tests often conducted to meet the needs of regulators in different countries.

These toxicity tests traditionally involve cruel tests on animals such as guinea pigs, rats, mice and rabbits. Animals are force fed, forced to inhale or injected with chemicals to see what dose will sicken or kill them.

We already know that many regulatory tests on animals can be fully replaced with non-animal approaches which provide high-quality information about the everyday products we use, and without causing suffering. We push for faster development of new non-animal test methods and wider use and acceptance of non-animal approaches.

Around the world there are many different systems of rules to manage chemicals. In the European Union, for example, chemicals are governed by a piece of legislation called REACH (the Registration, Evaluation, Authorisation and Restriction of Chemicals). In the UK, following Brexit, the Government is developing their own system. Our experts work within all these global regimes to drive down animal testing. Raising the voice of concerned citizens, we put pressure on governments and policy makers to end the testing of chemicals on animals.

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Bottles

Our focus.
What we’re doing

We push for faster development of new non-animal test methods, wider use and acceptance of non-animal approaches, and the avoidance of testing on animals. We put pressure on governments and policy makers to end the tests on animals that can be stopped immediately, and to drive the phase out of all others.
We are expert stakeholders, representing animals at bodies such as the European Commission, the European Centre for the Validation of Alternative Methods and the European Chemicals Agency (ECHA). We drive for an evolution in testing associated with so many of the familiar items we use every day – from the testing of components used to make a fridge-freezer, to the fuel we put in our cars, or the products we use to clean our houses.

Working to drive animal testing out of chemicals safety worldwide we:

  • Challenge governments, policy makers, regulatory authorities and companies to phase-out the testing of chemicals on animals. We push for accelerated development of new non-animal approaches for the testing of chemical substances and promote the widest possible use of non-animal methods for generating high-quality safety information ensuring outdated animal tests are eliminated everywhere.
  • Promote the acceptance of non-animal approaches for testing chemicals by regulatory authorities, including through our work as part of ICAPO (the International Council of Animal Protection for the OECD) where we contribute to the preparation of internationally agreed guidelines for testing.
  • Mobilise compassionate citizens through high-profile campaigns.
  • Encourage brands manufacturing household products to go cruelty-free, working in partnership to enable them to become approved by Cruelty Free International, driving animal testing out of industry and the everyday products we use.
Eric McCormack

Our achievements

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What’s next

Chemicals laws continue to develop around the world. In Europe, following our successful European Citizens Initiative, the European Commission has promised to start planning the phase out of animal testing for chemicals. We await the planned roadmap and stand ready to ensure that real change happens. In the UK we are pushing the government to ensure a modern cruelty-free chemicals testing regime and in the US we work to ensure that non-animal methods are prioritised and used. Challenging governments, authorities and companies we are driving real change and bringing forward the day when outdated animal tests are eliminated everywhere.

Get involved

We have made progress together but there is more to do to finally end the cruelty of testing chemicals on animals everywhere and forever. When you raise your voice governments listen. When you reward progressive brands more go cruelty-free. When you support us our experts can make sure that animal tests are driven out of chemicals regimes. Please help us consign animal testing to the history books.

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News & Updates

Europe takes action to phase out animal testing of Botox products
Europe takes action to phase out animal testing of Botox products

Europe takes action to phase out animal testing of Botox products

August 19, 2026
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Building on FDA Modernization to Replace Animal Tests

Building on FDA Modernization to Replace Animal Tests

August 14, 2026
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We take our fight for freedom of information to the Royal Courts of Justice

We take our fight for freedom of information to the Royal Courts of Justice

July 29, 2026
Andy Burnham
Government must speed-up implementation of animal testing strategy

Government must speed-up implementation of animal testing strategy

July 23, 2026
2.54 million animal tests in Great Britain in 2025 
2.54 million animal tests in Great Britain in 2025

2.54 million animal tests in Great Britain in 2025

July 9, 2026
New dashboard will reduce global animal testing
New dashboard will reduce global animal testing

New dashboard will reduce global animal testing

July 3, 2026